{"id":2916,"date":"2018-07-05T06:00:55","date_gmt":"2018-07-04T21:00:55","guid":{"rendered":"https:\/\/www.muscle-hypertrophy.com\/?p=2916"},"modified":"2018-07-05T07:54:43","modified_gmt":"2018-07-04T22:54:43","slug":"%e3%83%88%e3%83%ac%e3%83%bc%e3%83%8b%e3%83%b3%e3%82%b0%e3%81%ae%e6%9c%80%e9%81%a9%e5%8c%96%ef%bc%9a%e5%ae%89%e5%85%a8%e3%81%aa%e7%ad%8b%e5%8a%9b%e3%83%88%e3%83%ac%e3%83%bc%e3%83%8b%e3%83%b3%e3%82%b0","status":"publish","type":"post","link":"https:\/\/www.muscle-hypertrophy.com\/?p=2916","title":{"rendered":"\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u6700\u9069\u5316\uff1a\u5b89\u5168\u306a\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u304a\u3051\u308b\u65b0\u3057\u3044\u9032\u5c55"},"content":{"rendered":"<p>\u3000<a href=\"https:\/\/www.muscle-hypertrophy.com\/?p=2740\" rel=\"noopener\" target=\"_blank\">\u4f4e\u5f37\u5ea6\u3068\u9ad8\u5f37\u5ea6\u3068\u306e\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u304a\u3051\u308b\u7b4b\u529b\u3068\u7b4b\u80a5\u5927\u306e\u9069\u5fdc\uff0c\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3068\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9<\/a>\u306b\u304a\u3044\u3066\u53c2\u8003\u6587\u732e\u306e\u4e00\u3064\u306b\u6319\u3052\u3089\u308c\u3066\u3044\u305f\u8ad6\u6587\u3092\u6284\u8a33\u3059\u308b\uff0e\u30ed\u30b7\u30a2\u304b\u3089\u306e\u7b4b\u751f\u691c\u3092\u542b\u3080\u8cb4\u91cd\u306a\u5831\u544a\u3067\u3042\u308b\uff0e\u3053\u306e\u3088\u3046\u306a\u4fb5\u8972\u7684\u306a\u691c\u67fb\u306f\u65e7\u5171\u7523\u570f\u3060\u304b\u3089\u53ef\u80fd\u306a\u306e\u304b\u3082\u77e5\u308c\u306a\u3044\uff0e<\/p>\n<p>\u3000\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u8ca0\u8377\u306e\u8efd\u91cd\u306e\u9055\u3044\u3067\u80a5\u5927\u3059\u308b\u7b4b\u7e4a\u7dad\u306e\u578b\u304c\u7570\u306a\u308b\uff0c\u3068\u3044\u3046\u5f15\u7528\u3060\u3051\u3092\u629c\u7c8b\u3059\u308b\u3064\u3082\u308a\u3060\u3063\u305f\u306e\u304c\uff0c\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u306b\u307e\u3067\u8a00\u53ca\u3057\u3066\u304a\u308a\uff0c\u307b\u307c\u5168\u8a33\u3068\u306a\u3063\u3066\u3057\u307e\u3063\u305f\uff0e\u4e8c\u9031\u9593\u3082\u304b\u304b\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u306f\u52b9\u7387\u304c\u60aa\u3059\u304e\u308b\u306e\u3060\u304c\uff0c\u3053\u3053\u306f\u52c9\u5f37\u3068\u601d\u3063\u3066\u6211\u6162\u3057\u3088\u3046\uff0e<\/p>\n<p><!--more--><\/p>\n<h3><a href=\"https:\/\/www.researchgate.net\/publication\/263071796_Optimization_of_training_New_developments_in_safe_strength_training\" rel=\"noopener\" target=\"_blank\">Optimization of Training: New Developments in Safe Strength Training (Human Physiology, 2013, Vol. 39, No. 5, pp. 511\u2013523)<\/a><\/h3>\n<h3>Abstract<\/h3>\n<p>The hypertrophic effect of strength training is known to be due to mechanical and metabolic stimuli. During exercises with the restricted blood supply of working muscles, i.e., under the conditions of intensified metabolic stress, the training effect may be achieved with much lower external loads (20% of one repetition maximum). The effects of 8 weeks of high intensity (80\u201385% of one repetition maximum) strength training were compared to low intensity (50% of one repetition maximum) training without relaxation. The high intensity strength training resulted in higher increases in strength and size of the exercised muscles than training without relaxation. During high intensity training, at the muscle cross section, an increase in the area occupied by type II fibers prevails; while, during training without relaxation, an increase in the area occupied by type I fibers prevails. An exercise session without relaxation leads to a more pronounced increase in the secretion of the growth hormone, insulin like growth factor 1, and cortisol. The expression of gene regulating myogenesis (Myostatin) is changed in different ways after a high intensity strength exercise session and after an exercise session without relaxation. Low intensity strength training (50% of one repetition maximum) without relaxation is an efficient way for inducing increases of the strength and size of the trained muscles. This low intensive type of training may be used in rehabilitation medicine, sports, and fitness.<\/p>\n<p>\u3000\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u80a5\u5927\u52b9\u679c\u306f\u6a5f\u68b0\u7684\u523a\u6fc0\u304a\u3088\u3073\u4ee3\u8b1d\u7684\u523a\u6fc0\u306b\u3088\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\uff0e\u8840\u6db2\u306e\u4f9b\u7d66\u3092\u5236\u9650\u3057\u305f\u904b\u52d5\u4e2d\uff0c\u4f8b\u3048\u3070\u4ee3\u8b1d\u30b9\u30c8\u30ec\u30b9\u306e\u5f37\u5316\u3055\u308c\u305f\u6761\u4ef6\u4e0b\u306a\u3069\u3067\u306f\uff0c\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u52b9\u679c\u306f\u3088\u308a\u6975\u7aef\u306b\u4f4e\u3044\u5916\u90e8\u8ca0\u8377 (20% 1RM) \u306b\u304a\u3044\u3066\u9054\u6210\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e8 \u9031\u9593\u306e\u9ad8\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (80-85% 1RM) \u306e\u52b9\u679c\u3068\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (50% 1RM) \u306e\u52b9\u679c\u3068\u3092\u6bd4\u8f03\u3057\u305f\uff0e\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u5f1b\u7de9\u306a\u3057\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3088\u308a\u3082\u7b4b\u529b\u304a\u3088\u3073\u904b\u52d5\u3057\u305f\u7b4b\u8089\u306e\u5927\u304d\u3055\u306b\u304a\u3044\u3066\u3088\u308a\u9ad8\u3044\u5897\u52a0\u3092\u3082\u305f\u3089\u3057\u305f\uff0e\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9593\uff0c\u7b4b\u65ad\u9762\u7a4d\u306b\u304a\u3044\u3066\u306f II \u578b\u7dda\u7dad\u306e\u9762\u7a4d\u304c\u512a\u5148\u7684\u306b\u5897\u52a0\u3057\u305f\uff0e\u4e00\u65b9\u3067\uff0c\u5f1b\u7de9\u306a\u3057\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9593\u306f I \u578b\u7dda\u7dad\u306e\u9762\u7a4d\u304c\u512a\u5148\u7684\u306b\u5897\u52a0\u3057\u305f\uff0e\u5f1b\u7de9\u306a\u3057\u306e\u904b\u52d5\u30bb\u30c3\u30b7\u30e7\u30f3\u3067\u306f\u6210\u9577\u30db\u30eb\u30e2\u30f3\uff0cIGF-1 \u304a\u3088\u3073\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5206\u6ccc\u304c\u3088\u308a\u9855\u8457\u306b\u5897\u52a0\u3059\u308b\uff0e\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\uff08\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\uff09\u306f\uff0c\u9ad8\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5f8c\u3068\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5f8c\u3068\u3067\u306f\uff0c\u7570\u306a\u308b\u7d4c\u8def\u3067\u767a\u73fe\u3059\u308b\uff0e\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (50% 1RM) \u306f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3057\u305f\u7b4b\u8089\u306e\u7b4b\u529b\u3068\u5927\u304d\u3055\u3092\u5897\u52a0\u3055\u305b\u308b\u52b9\u679c\u7684\u306a\u65b9\u6cd5\u3067\u3042\u308b\uff0e\u3053\u306e\u4f4e\u5f37\u5ea6\u578b\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u533b\u5b66\uff0c\u30b9\u30dd\u30fc\u30c4\u304a\u3088\u3073\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u306b\u6d3b\u7528\u3057\u3046\u308b\uff0e<\/p>\n<h3>Keywords<\/h3>\n<p>strength training, skeletal muscle, muscle fibers, anabolic hormones, gene expression<\/p>\n<h3>MATERIALS AND METHODS<\/h3>\n<p>\u30008-10 \u9031\u9593\u306e\u671f\u9593\u3067\u9ad8\u5f37\u5ea6\u7fa4\u3068\u3057\u3066 80-85% 1RM \u304a\u3088\u3073\uff0c\u4f4e\u5f37\u5ea6\u7fa4\u3068\u3057\u3066 50-70% 1RM \u5f1b\u7de9\u306a\u3057\u3068\u3057\uff0c\u7a2e\u76ee\u306f\u30ec\u30c3\u30b0\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3\uff08L \u30b7\u30ea\u30fc\u30ba\uff09\u3068\u30cb\u30fc\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3\uff08K \u30b7\u30ea\u30fc\u30ba\uff09\uff0c\u7b4b\u8089\u306e\u5f62\u614b\u5b66\u7684\u5909\u5316\u3092\u8a08\u6e2c\u3059\u308b\u306e\u306b MRI \u3092\u7528\u3044\uff0c\u751f\u5316\u5b66\u7684\u691c\u67fb\u304a\u3088\u3073\u5185\u5206\u6ccc\u5b66\u7684\u691c\u67fb\uff0c\u3055\u3089\u306b\u7b4b\u751f\u691c\u3092\u65bd\u884c\u3057\u305f\uff0e<\/p>\n<p>\u3000I \u578b\u304a\u3088\u3073 II \u578b\u7b4b\u7dda\u7dad (MFI, MFII) \u306b\u3088\u308a\u5360\u3081\u3089\u308c\u308b\u9762\u7a4d\u306f\u5916\u5074\u5e83\u7b4b\u306e\u65ad\u9762\uff0c\u3064\u307e\u308a\u7b4b\u8089\u5185\u306e\u3053\u306e\u578b\u306e\u7dda\u7dad\u306e\u7d44\u6210\u306e\u5272\u5408\u306b\u3053\u306e\u578b\u306e\u7b4b\u7dda\u7dad\u65ad\u9762\u7a4d\u3092\u304b\u3051\u3066\u6c42\u3081\u305f\uff0e<\/p>\n<p>\u3000\u63a1\u8840\u691c\u67fb\u306f\u521d\u671f\uff08\u7b2c 2 \u9031\uff09\u304a\u3088\u3073\u5f8c\u671f\uff08\u7b2c 7 \u9031\uff09\u306b\u65bd\u884c\u3057\u305f\uff0e\u6bd4\u8f03\u306e\u305f\u3081\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u4f11\u606f\u6642\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e 1 \u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u306b\u63a1\u8840\u3057\u305f\uff0e\u9805\u76ee\u306f\u4e73\u9178\uff0c\u6210\u9577\u30db\u30eb\u30e2\u30f3 (GH), \u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50 (IGF-1), \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u304a\u3088\u3073\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u3067\u3042\u308b\uff0e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u524d\u3068 18 \u6642\u9593\u5f8c\u306b\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bc\u6d3b\u6027 (CK), \u5fc3\u7b4b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0 (CK-MB) \u3092\u6e2c\u5b9a\u3057\u305f\uff0e\u6a2a\u7d0b\u7b4b\u7531\u6765\u306e CK (CK-MM) \u306f\u8a08\u7b97\u3067\u6c42\u3081\u305f\uff0e<\/p>\n<p>\u3000\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306e\u5909\u5316\u306f 1 \u30bb\u30c3\u30b7\u30e7\u30f3\u524d, 5 \u6642\u9593\u5f8c, 22 \u6642\u9593\u5f8c\u306b\u884c\u3044\uff0c\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0 PCR \u6cd5\u3092\u7528\u3044\u305f\uff0e<\/p>\n<p>\u3000\u30ef\u30fc\u30af\u30a2\u30a6\u30c8\u5f53\u65e5\u306f\u88ab\u9a13\u8005\u306f\u901a\u5e38\u306e\u671d\u98df\u3092\u6442\u3063\u3066 1 \u6642\u9593\u5f8c\u306b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u3092\u884c\u3044\uff0c\u901a\u5e38\u306e\u663c\u98df\u3092\u6442\u3063\u305f\uff0e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u524d\u3068 15 \u5206\u5f8c\u306b\u9759\u8108\u8840\u3092\u63a1\u8840\u3057\u3066\u30db\u30eb\u30e2\u30f3\u5024\u3092\u6e2c\u5b9a\u3057\u305f\uff0e3 \u30bb\u30c3\u30c8\u5f8c\uff0c5 \u30bb\u30c3\u30c8\u5f8c\uff0c8 \u30bb\u30c3\u30c8\u5f8c\u306b\u6307\u306e\u6bdb\u7d30\u8840\u7ba1\u304b\u3089\u63a1\u8840\u3057\u3066\u4e73\u9178\u5024\u3068\u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u305f\uff0e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u524d\uff0c5 \u6642\u9593\u5f8c\uff0c22 \u6642\u9593\u5f8c\u306b micro-biopsy technique \u3092\u7528\u3044\u3066\u5916\u5074\u5e83\u7b4b\u306e\u7b4b\u7d44\u7e54\u6a19\u672c\u3092\u63a1\u53d6\u3057\u305f\uff0e<\/p>\n<p>\u3000\u7b4b\u8089\u306e\u5f62\u614b\u8a08\u6e2c\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u63a8\u5b9a\u3059\u308b\u306e\u306b\u5927\u817f\u56db\u982d\u7b4b\u3068\u5927\u6bbf\u7b4b\u3092 MRI \u3067\u8a08\u6e2c\u3057\u305f\uff0e<\/p>\n<p>\u3000I \u578b\u304a\u3088\u3073 II \u578b\u7b4b\u7dda\u7dad\u306e\u65ad\u9762\u7a4d\u3092\u5916\u5074\u5e83\u7b4b\u306e needle biopsy technique (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/6048626\" rel=\"noopener\" target=\"_blank\">29<\/a>) \u306b\u3088\u308a\u7b4b\u751f\u691c\u6a19\u672c\u6a2a\u65ad\u9762\u3092\u8a55\u4fa1\u3057\u305f\uff0e\u5206\u6790\u524d\u306b -20 &deg;C \u3067\u30de\u30a4\u30af\u30ed\u30c8\u30fc\u30e0\u3092\u7528\u3044\u3066\u539a\u3055 5 &micro;m \u306b\u51cd\u7d50\u5207\u7247\u306b\u8584\u5207\u3057\uff0c\u7b4b\u7dda\u7dad\u306b\u6cbf\u3063\u3066\u9023\u7d9a\u5207\u7247\u3092\u5782\u76f4\u306b\u7a4d\u307f\u4e0a\u3052\u305f\uff0eI \u578b\u304a\u3088\u3073 II \u578b\u7b4b\u7dda\u7dad\u306f NCL-MHCf (a+b) \u304a\u3088\u3073 NCL-MHCs \u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53 (Novocastra laboratories) \u3092\u7528\u3044\u305f\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u306b\u3088\u308a\u691c\u51fa\u3057\u305f\uff0e\u305d\u3057\u3066\uff0cFITS \u3067\u6a19\u8b58\u3057\u305f\u4e8c\u6b21\u6297\u4f53\u3092\u7528\u3044\u305f\uff0e\u8a08\u6e2c\u306f\u30ab\u30fc\u30eb\u30c4\u30a1\u30a4\u30b9\u88fd Axiovert-200 \u9855\u5fae\u93e1\u3067\u884c\u3063\u305f\uff0e\u5404\u3005\u306e\u7d44\u7e54\u6a19\u672c\u306b\u3064\u304d\uff0c\u305d\u308c\u305e\u308c\u306e\u578b\u306b\u3064\u304d\u6700\u4f4e 100 \u306e\u7b4b\u7dda\u7dad\u3092\u8a08\u6e2c\u3057\u305f\uff0e<\/p>\n<p>\u3000\u7b4b\u7d44\u7e54\u304b\u3089\u306e RNA \u5358\u96e2\u306f\u7c73\u56fd Invitrogen \u88fd\u306e TRIZOL \u30bb\u30c3\u30c8\u306b\u3066\u884c\u3063\u305f\uff0e\u76f8\u88dc\u7684 DNA \u306f\u30ed\u30b7\u30a2\u88fd Sileks \u30bb\u30c3\u30c8\u306b\u3066\u5f97\u305f\uff0e<\/p>\n<p>\u3000\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u9023\u9396\u53cd\u5fdc\uff0e\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0 PCR \u6cd5\u306f\u30ed\u30b7\u30a2 Synthol \u88fd\u306e SybrGreen \u30bb\u30c3\u30c8\u306b\u3066\u884c\u3063\u305f\uff0e\u6a19\u672c\u4e2d\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50 (IGF-1Ea) \u304a\u3088\u3073\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u91cf\u3092\u691c\u51fa\u3057\u305f\uff0e\u53c2\u7167\u907a\u4f1d\u5b50\u3068\u3057\u3066\u30ea\u30dc\u30be\u30fc\u30e0\u30bf\u30f3\u30d1\u30af P<sub>0<\/sub> \u304a\u3088\u3073 &beta; \u30a2\u30af\u30c1\u30f3\u3092\u7528\u3044\u305f\uff0e\u6a19\u7684\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u5909\u5316\u306f\u6587\u732e <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11328886\" rel=\"noopener\" target=\"_blank\">30<\/a> \u306b\u5f93\u3063\u3066\u691c\u51fa\u3057\uff0c\u6a19\u7684\u907a\u4f1d\u5b50\u3068\u53c2\u7167\u907a\u4f1d\u5b50\u306e\u53cd\u5fdc\u52b9\u7387\u306f\u6a19\u6e96\u66f2\u7dda\u306b\u3088\u308a\u8a08\u7b97\u3057\u305f\uff0e<\/p>\n<h3>RESULTS AND DISCUSSION<\/h3>\n<h4>Strength training of the leg extensors (L series)<\/h4>\n<p>\u3000\u4e21\u8005\u306e\u578b\u306e\u7b4b\u7dda\u7dad\u306f\u9ad8\u5f37\u5ea6\u306e\u7b4b\u53ce\u7e2e\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14328454\" rel=\"noopener\" target=\"_blank\">32<\/a>). \u540c\u6642\u306b\u6b21\u306e\u70b9\u3082\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u308b\uff0e\u3064\u307e\u308a\uff0c\u4f1d\u7d71\u7684\u306a\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f I \u578b\u7b4b\u7dda\u7dad\u3088\u308a\u3082 II \u578b\u7b4b\u7dda\u7dad\u306b\u304a\u3044\u3066\u6fc0\u3057\u3044\u80a5\u5927\u3092\u3082\u305f\u3089\u3059 (33,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/1835816\" rel=\"noopener\" target=\"_blank\">34<\/a>,<a href=\"https:\/\/link.springer.com\/article\/10.1007\/BF00952534\" rel=\"noopener\" target=\"_blank\">35<\/a>,<a href=\"https:\/\/link.springer.com\/article\/10.1007\/BF00572189\" rel=\"noopener\" target=\"_blank\">36<\/a>). \u304a\u305d\u3089\u304f\uff0c\u305d\u306e\u7406\u7531\u306f\u9ad8\u5f37\u5ea6\u306e\u7b4b\u8089\u306e\u4ed5\u4e8b\u304c II \u578b\u7b4b\u7dda\u7dad\u306b\u304a\u3044\u3066 I \u578b\u7b4b\u7dda\u7dad\u3088\u308a\u3082\u660e\u767d\u306a\u4ee3\u8b1d\u6027\u5909\u5316\u3092\u3082\u305f\u3089\u3059\u305f\u3081\u3067\u3042\u308d\u3046\uff0e\u3053\u308c\u306b\u3088\u308a mTORC1 \u304a\u3088\u3073 ERK1\/2 \u30b7\u30b0\u30ca\u30eb\u7d4c\u8def\u306e\u3088\u308a\u5927\u304d\u306a\u6d3b\u6027\u5316\u304c\u3082\u305f\u3089\u3055\u308c\uff0c\u30bf\u30f3\u30d1\u30af\u5408\u6210\u3092\u8abf\u6574\u3059\u308b (<a href=\"https:\/\/pdfs.semanticscholar.org\/f366\/17382b601f4e5f86c9c63ef0ff38cd7be36b.pdf\" rel=\"noopener\" target=\"_blank\">37<\/a>,<a href=\"https:\/\/www.physiology.org\/doi\/abs\/10.1152\/japplphysiol.91243.2008\" rel=\"noopener\" target=\"_blank\">38<\/a>). \u6211\u3005\u306e\u8a66\u9a13 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17465271\" rel=\"noopener\" target=\"_blank\">39<\/a>) \u306b\u304a\u3044\u3066\u306f LC \u7fa4\uff08\u30ec\u30c3\u30b0\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3<strong>\u9ad8\u5f37\u5ea6\u7fa4<\/strong>\uff09<strong>\u306b\u304a\u3044\u3066\uff0c\u4f5c\u52d5\u7b4b\u3067\u3042\u308b\u5916\u5074\u5e83\u7b4b\u306b\u304a\u3051\u308b II \u578b\u7b4b\u7dda\u7dad\u306e\u5360\u3081\u308b\u9762\u7a4d\u306e\u5897\u52a0\u306f 23 % \u3067\u3042\u3063\u305f\uff0e\u4e00\u65b9\u3067 I \u578b\u7b4b\u7dda\u7dad\u306b\u3064\u3044\u3066\u306f\u5909\u5316\u306f\u306a\u304f<\/strong>\uff0c\u305d\u306e\u3053\u3068\u306f\u6587\u732e\u306e\u30c7\u30fc\u30bf\u3068\u3082\u4e00\u81f4\u3059\u308b\uff0e\u3057\u304b\u3057\uff0c<strong>\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5f8c\u306b<\/strong>\uff0c\u5b9a\u6027\u7684\u306a\u5dee\u7570\u306e\u5909\u5316\u304c\u4ee5\u4e0b\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u306b\u304a\u3044\u3066\u8a8d\u3081\u3089\u308c\u305f\uff0e\u3059\u306a\u308f\u3061\uff0c<strong>II \u578b\u7b4b\u7dda\u7dad\u306e\u5360\u3081\u308b\u9762\u7a4d\u306b\u306f\u5909\u5316\u304c\u306a\u304b\u3063\u305f\u4e00\u65b9\u3067\uff0cI \u578b\u7b4b\u7dda\u7dad\u306e\u5360\u3081\u308b\u9762\u7a4d\u304c 18 % \u5897\u52a0\u3057\u3066\u3044\u305f<\/strong> (<strong>Table 1<\/strong>). \u6211\u3005\u306f\u6b21\u306e\u3088\u3046\u306b\u4eee\u5b9a\u3057\u305f\uff0e\u3064\u307e\u308a\uff0c\u7b4b\u7dda\u7dad\u306b\u304a\u3044\u3066\u30de\u30fc\u30af\u3057\u305f\u4ee3\u8b1d\u30b9\u30c8\u30ec\u30b9\u304c\uff0c\u7b4b\u80a5\u5927\u306e\u30d7\u30ed\u30bb\u30b9\u3092\u958b\u59cb\u3055\u305b\u308b\u56e0\u5b50\u306e\u4e00\u3064\u306b\u306a\u308a\u3046\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\uff0eI \u578b\u7b4b\u7dda\u7dad\u306b\u304a\u3044\u3066\u30de\u30fc\u30af\u3057\u305f\u4ee3\u8b1d\u30b7\u30d5\u30c8\u3092\u9054\u6210\u3059\u308b\u306e\u306f\u96e3\u3057\u3044 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/665258\" rel=\"noopener\" target=\"_blank\">40<\/a>). \u3068\u3044\u3046\u306e\u3082\uff0c\u3053\u306e\u578b\u306e\u7b4b\u7dda\u7dad\u306f\u9ad8\u3044\u9178\u5316\u96fb\u4f4d\u3092\u6709\u3057\u3066\u3044\u308b\u304b\u3089\u3067\u3042\u308b\uff0e\u3057\u304b\u3057\u4ee5\u4e0b\u306e\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\uff0e\u3064\u307e\u308a\uff0c\u7b49\u5c3a\u6027\u53ce\u7e2e\uff08\u7b4b\u7dca\u5f35\u306b\u3088\u308b\u8840\u6d41\u963b\u5bb3\u6761\u4ef6\u4e0b\uff09\u306b\u304a\u3044\u3066\uff0c25%, 50%, 75% 1RM \u306e\u5f37\u5ea6\u3067\u5916\u5074\u5e83\u7b4b\u304c\u75b2\u52b4\u56f0\u618a\u3057\u305f\u6642\u306e\u6700\u5927\u4e73\u9178\u6fc3\u5ea6\u3092\u8a18\u9332\u3059\u308b\u3068\uff0c50% 1 RM \u306e\u6642\u306b I \u578b\u7b4b\u7dda\u7dad\u306b\u304a\u3051\u308b\u4e73\u9178\u6fc3\u5ea6\u304c\u6700\u5927\u3068\u306a\u3063\u305f (41,<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/j.1748-1716.1977.tb10374.x\" rel=\"noopener\" target=\"_blank\">42<\/a>). \u660e\u3089\u304b\u306b\u3053\u308c\u306f\u4ee5\u4e0b\u306e\u4e8b\u5b9f\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308b\uff0e\u3064\u307e\u308a\uff0c<strong>dimension \u306e\u539f\u7406<\/strong>\u306b\u3088\u308b\u3068\uff0c\u3053\u306e\u7279\u5fb4\u306e\u4ed5\u4e8b\u306f\u4e3b\u306b I \u578b\u7b4b\u7dda\u7dad\u304c\u5f93\u4e8b\u3057\u3066\u3044\u308b\u306b\u9055\u3044\u306a\u304f (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14328454\" rel=\"noopener\" target=\"_blank\">32<\/a>), \u305d\u308c\u306f\u3064\u307e\u308a\uff0c\u8840\u6d41\u5236\u9650\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308a\uff0c\u89e3\u7cd6\u7cfb\u306e\u6d3b\u6027\u5316\u304c\u8d77\u304d\u3066\u3044\u308b\u3053\u3068\u306b\u3088\u308b\uff0e\u3053\u306e\u3053\u3068\u306f\u6b21\u306e\u60f3\u5b9a\u306e\u571f\u53f0\u3068\u306a\u308b\uff0e\u3064\u307e\u308a\uff0c\u5f1b\u7de9\u306a\u3057\u306e 50% 1RM \u306e\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\uff0c\u7b49\u5c3a\u6027\u904b\u52d5\u3068\u540c\u69d8\u306b\uff0cI \u578b\u7b4b\u7dda\u7dad\u304c\u5b9f\u884c\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\uff0c\u75b2\u52b4\u56f0\u618a\u306b\u81f3\u308b\u6642\u306b\u30de\u30fc\u30af\u3057\u305f\u4ee3\u8b1d\u30b7\u30d5\u30c8\u304c\u89b3\u6e2c\u3055\u308c\u308b\uff0e\u7279\u7b46\u3059\u3079\u304d\u3053\u3068\u3060\u304c\uff0cLE \u7fa4\u306b\u304a\u3044\u3066\u306f\u5404\u30bb\u30c3\u30c8\u306e\u7d42\u4e86\u306f\u88ab\u9a13\u8005\u306e\u4f5c\u52d5\u7b4b\u306e\u3072\u3069\u3044\u75b2\u52b4\u306b\u4ed8\u968f\u3057\u305f\u3082\u306e\u3067\u3042\u3063\u305f\uff0e\u3068\u540c\u6642\u306b\uff0c\u89e3\u7cd6\u7cfb\u6d3b\u6027\u5316\u306e\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308b\u8840\u4e2d\u4e73\u9178\u6fc3\u5ea6\u306f LE \u7fa4\u306e\u30bb\u30c3\u30b7\u30e7\u30f3\u3067\u306f LC \u7fa4\u3088\u308a\u3082\u9ad8\u3044\u5024\u3092\u793a\u3057\u305f\uff0e<\/p>\n<figure id=\"attachment_2947\" aria-describedby=\"caption-attachment-2947\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Table1.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Table1-300x147.png\" alt=\"\" width=\"300\" height=\"147\" class=\"size-medium wp-image-2947\" srcset=\"https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Table1-300x147.png 300w, https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Table1-768x375.png 768w, https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Table1-1024x500.png 1024w, https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Table1.png 1443w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-2947\" class=\"wp-caption-text\">Table 1. The comparison of the effects the traditional high-intensive strength training (control groups, C) and training without muscle relaxation (experimental groups, E) during leg extension series (L series), knee extension series (K series), and leg extension series, when the group trained with middle intensity (M series)<\/figcaption><\/figure>\n<h4>Strength training of the knee extensors (K series)<\/h4>\n<p>\u300080-85% 1RM \uff08\u5bfe\u7167\u7fa4, KC \u7fa4\uff09\u306e\u5f37\u5ea6\u306b\u3088\u308b\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u3092\u5f1b\u7de9\u306a\u3057\u306e 50% 1RM \u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7fa4\uff08\u4ecb\u5165\u7fa4, KE \u7fa4\uff09\u3068\u6bd4\u8f03\u3057\u305f\uff0e10 \u9031\u9593\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30b5\u30a4\u30af\u30eb\u671f\u9593\u306b\u304a\u3051\u308b KC \u7fa4\u3068 KE \u7fa4\u306e\u7dcf\u4ed5\u4e8b\u91cf\u306e\u9055\u3044\u306f 2 \u500d\u4ee5\u4e0a\u306b\u306a\u3063\u305f (<strong>Table 1<\/strong>). \u540c\u6642\u306b\uff0c\u819d\u4f38\u5c55\u7b4b\u306e 1RM \u306e\u5897\u52a0\u306b\u9055\u3044\u306f\u898b\u3089\u308c\u305a, KC \u7fa4\u3068 KE \u7fa4\u3067\u305d\u308c\u305e\u308c 29%, 24% \u3067\u3042\u3063\u305f (<strong>Table 1<\/strong>). <\/p>\n<p>\u3000\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u671f\u9593\u306b\u304a\u3051\u308b 1RM \u5897\u52a0\u306e\u89e3\u6790\u3067\u306f L \u30b7\u30ea\u30fc\u30ba\u3068 K \u30b7\u30ea\u30fc\u30ba\u3067\u6709\u610f\u5dee\u304c\u8a8d\u3081\u3089\u308c\u305f\uff0eK \u30b7\u30ea\u30fc\u30ba\u3067\u306f\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e 1RM \u306e\u5897\u52a0\u306f\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3088\u308a\u3082\u8457\u660e\u306b\u5927\u304d\u304b\u3063\u305f (35% vs. 21%). \u4e00\u65b9\u3067 K \u30b7\u30ea\u30fc\u30ba\u306b\u304a\u3044\u3066\u306f\u8a18\u9332\u3055\u308c\u305f\u7fa4\u9593\u306b\u5dee\u7570\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f (29% vs. 24%). \u660e\u3089\u304b\u306b\uff0c\u3053\u308c\u3089\u306e\u9055\u3044\u306f\u4e0a\u8ff0\u3057\u305f\u4e0b\u80a2\u3068\u819d\u306e\u7b4b\u8089\u306e\u751f\u4f53\u529b\u5b66\u7684\u7279\u5fb4\uff0c\u3059\u306a\u308f\u3061\uff0c\u7b4b\u8089\u9593\u306e\u8ca0\u8377\u306e\u518d\u5206\u914d\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\uff0e<\/p>\n<p>\u300010 \u9031\u9593\u306b\u308f\u305f\u308b\u819d\u4f38\u5c55\u7b4b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\uff0c\u5916\u5074\u5e83\u7b4b\u65ad\u9762\u7a4d\u306b\u5360\u3081\u308b\u7570\u306a\u308b\u578b\u306e\u7b4b\u7dda\u7dad\u306e\u9762\u7a4d\u3092\u8a55\u4fa1\u3059\u308b\u3068, KC \u7fa4\u3067\u306e II \u578b\u7b4b\u7dda\u7dad\u3068 KE \u7fa4\u306e I \u578b\u7b4b\u7dda\u7dad\u3068\u306f\u4f3c\u305f\u3088\u3046\u306a\u5897\u52a0\u3092\u793a\u3057\u3066\u3044\u308b\u306e\u304c\u5206\u304b\u308b (<strong>Table 1<\/strong>). \u3053\u308c\u306f L \u30b7\u30ea\u30fc\u30ba\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u3082\u89b3\u6e2c\u3055\u308c\u305f\u7d50\u679c\u306b\u3088\u304f\u5408\u81f4\u3059\u308b\uff0e<\/p>\n<p>\u3000\u3086\u3048\u306b\uff0c\u819d\u3068\u4e0b\u80a2\u4f38\u5c55\u7b4b\u306e\u9577\u671f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u306e\u6bd4\u8f03\u3092\u3082\u3068\u306b\uff0c\u6211\u3005\u306f\u6b21\u306e\u3088\u3046\u306b\u7d50\u8ad6\u4ed8\u3051\u305f\uff0e(1) \u30ec\u30c3\u30b0\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3\u306b\u304a\u3051\u308b\u819d\u4f38\u5c55\u7b4b\u3068\u81c0\u90e8\u4f38\u5c55\u7b4b\u306e\u80a5\u5927\u306e\u7a0b\u5ea6\u306f\u904b\u52d5\u306e\u751f\u4f53\u529b\u5b66\u306b\u4f9d\u5b58\u3059\u308b. (2) \u7b4b\u8089\u9593\u306e\u8ca0\u8377\u306e\u518d\u5206\u914d\u306e\u7d50\u679c\u3068\u3057\u3066\uff0c\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u3067\u306e\u30ec\u30c3\u30b0\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3\u306b\u304a\u3051\u308b\u7b4b\u529b\u5897\u52a0\u306f\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3088\u308a\u3082\u52a3\u308b. (3) \u819d\u4f38\u5c55\u7b4b\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u4f8b\u3068\u3057\u3066\uff0c\u5f1b\u7de9\u306a\u3057\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3068\u540c\u7b49\u306e\u819d\u4f38\u5c55\u7b4b\u306e\u7b4b\u529b\u5897\u52a0\u306b\u81f3\u3063\u305f\u4f8b\u3082\u3042\u308b. (4) \u819d\u4f38\u5c55\u7b4b\u306e\u5f1b\u7de9\u306a\u3057\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\uff0c\u30ec\u30c3\u30b0\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3\u540c\u69d8\uff0c\u7b4b\u529b\u5897\u52a0\u3092\u3082\u305f\u3089\u3057\uff0c\u305d\u308c\u306f\u4e3b\u306b I \u578b\u7b4b\u7dda\u7dad\u306e\u80a5\u5927\u306b\u3088\u308b\uff0e<\/p>\n<h4>Strength training of medium-intensity without relaxation (M series)<\/h4>\n<p>\uff08\u7565\uff09<\/p>\n<h4>An increase in the muscle mass and strength during low-intensity training without relaxation is related to hormonal adaptation<\/h4>\n<p>\u3000\u4e0a\u8ff0\u3057\u305f\u3088\u3046\u306b\uff0c\u7b4b\u80a5\u5927\u306f\u6a5f\u68b0\u7684\u304a\u3088\u3073\u4ee3\u8b1d\u7684\u56e0\u5b50\u306b\u3088\u308a\u6d3b\u6027\u5316\u3055\u308c\u308b\uff0e\u4e21\u8005\u306e\u56e0\u5b50\u306f\uff0c\u7b4b\u7dda\u7dad\u306b\u4f5c\u7528\u3057\u3066\u76f4\u63a5\u7684\u304b\uff0c\u307e\u305f\u306f\u540c\u5316\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u5897\u52a0\u3092\u4ecb\u3057\u3066\u9593\u63a5\u7684\u306b\u30bf\u30f3\u30d1\u30af\u5408\u6210\u3092\u6d3b\u6027\u5316\u3055\u305b\u308b\uff0e\u3053\u308c\u3089\u306e\u56e0\u5b50\u306e\u3046\u3061\uff0c\u6a5f\u68b0\u7684\u304b\u4ee3\u8b1d\u7684\u304b\uff0c\u3044\u305a\u308c\u304c\u91cd\u8981\u306a\u306e\u304b\u3068\u3044\u3046\u7591\u554f\u306b\u7b54\u3048\u3088\u3046\u3068\u8a66\u307f\uff0c\u7570\u306a\u308b\u30bf\u30a4\u30d7\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u969b\u306b\uff0c\u7b4b\u6d3b\u52d5\u306e\u30db\u30eb\u30e2\u30f3\u5fdc\u7b54\u3092\u60f9\u8d77\u3057\uff0c\u7b4b\u7d44\u7e54\u306b\u304a\u3051\u308b\u80a5\u5927\u6027\u5909\u5316\u306e\u6a5f\u5e8f\u3092\u5b9a\u7fa9\u3057\u3088\u3046\u3068\u3057\u305f\uff0e<\/p>\n<p>\u3000\u6210\u9577\u30db\u30eb\u30e2\u30f3\u6fc3\u5ea6\u306e\u5897\u52a0\u304c Ia \u7b4b\u6c42\u5fc3\u6027\u795e\u7d4c\u6d3b\u6027\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3042\u308b (<a href=\"https:\/\/pdfs.semanticscholar.org\/7fa2\/7d80fece97b7fc044e021d31e514507ce654.pdf\" rel=\"noopener\" target=\"_blank\">43<\/a>). \u3057\u304b\u3057\uff0c\u591a\u304f\u306e\u8457\u8005\u306f\u540c\u5316\u30db\u30eb\u30e2\u30f3\u6fc3\u5ea6\u5897\u52a0\u304c\u4f5c\u52d5\u7b4b\u3067\u306e\u4ee3\u8b1d\u5909\u5316\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3066\u3044\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11500963\" rel=\"noopener\" target=\"_blank\">8<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9268962\" rel=\"noopener\" target=\"_blank\">9<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8175595\" rel=\"noopener\" target=\"_blank\">44<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7775344\" rel=\"noopener\" target=\"_blank\">45<\/a>). \u5b9f\u969b\uff0c\u56db\u80a2\u306e\u865a\u8840\u306f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304a\u3088\u3073\u597d\u6c17\u6027\u904b\u52d5\u6642\u306e\u30db\u30eb\u30e2\u30f3\u5fdc\u7b54\u3092\u5897\u5f37\u3055\u305b\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9650736\" rel=\"noopener\" target=\"_blank\">10<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10642363\" rel=\"noopener\" target=\"_blank\">20<\/a>). <\/p>\n<p>\u3000\u6211\u3005\u306e\u8a66\u9a13 (<a href=\"https:\/\/www.researchgate.net\/publication\/6697900_Hormonal_adaptation_determines_the_increase_in_muscle_mass_and_strength_during_low-intensity_strength_training_without_relaxation\" rel=\"noopener\" target=\"_blank\">46<\/a>) \u3067\u306f\uff0c\u5f1b\u7de9\u306a\u3057\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u304a\u3051\u308b\u4f5c\u52d5\u7b4b\u306e\u8840\u6db2\u4f9b\u7d66\u306e\u5236\u9650\u306f\u540c\u5316\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u3092\u523a\u6fc0\u3059\u308b\u3068\u4eee\u5b9a\u3057\u305f\uff0e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30c8\u30b3\u30eb\u306f\u4e0a\u8ff0\u3057\u305f\u8a66\u9a13\u3067\u306e L \u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3068\u540c\u69d8\u3068\u3057\u305f (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17465271\" rel=\"noopener\" target=\"_blank\">39<\/a>). <\/p>\n<p>\u3000\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (85% 1RM) \u3068\u5f1b\u7de9\u306a\u3057\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (50% 1RM) \u3068\u3067\u306f\u8840\u4e2d\u4e73\u9178\u6fc3\u5ea6\u306e\u5909\u5316\uff0c\u304a\u3088\u3073\u7b4b\u539f\u6027\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bc\u6d3b\u6027\u306b\u7570\u306a\u308b\u7d50\u679c\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u5206\u304b\u3063\u305f\uff0e\u4e73\u9178\u306f\u89e3\u7cd6\u7cfb\u306e\u6700\u7d42\u7523\u7269\u3067\u3042\u308b\uff0e\u3086\u3048\u306b\uff0c\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u304a\u3051\u308b\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\u306f\u4e3b\u306b\u5acc\u6c17\u6027\u7d4c\u8def\u306b\u3088\u308a\uff0c\u8840\u4e2d\u4e73\u9178\u30ec\u30d9\u30eb\u306f\u4f5c\u52d5\u7b4b\u306b\u304a\u3051\u308b\u4ee3\u8b1d\u904e\u7a0b\u306e\u5f37\u5ea6\u3092\u9593\u63a5\u7684\u306b\u793a\u3057\u3066\u3044\u308b\uff0e\u4e88\u60f3\u901a\u308a\uff0c\u4f5c\u52d5\u7b4b\u3078\u306e\u8840\u6db2\u4f9b\u7d66\u306e\u906e\u65ad\u306f\u8840\u4e2d\u4e73\u9178\u6fc3\u5ea6\u306e\u8457\u660e\u306a\u4e0a\u6607\u3092\u4f34\u3063\u305f\uff0e8 \u9031\u9593\u306e\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u671f\u9593\u306e\u958b\u59cb\u6642\uff08\u7b2c 2 \u9031\u4e2d\uff09\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u306b\uff0c\u4f1d\u7d71\u7684\u306a\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7fa4\uff08C \u7fa4\uff09\u3067\u306e\u8840\u4e2d\u4e73\u9178\u6fc3\u5ea6\u306f 6.3 mmol\/L \u3067\u3042\u3063\u305f\uff0e\u3057\u304b\u3057\uff0c\u5f1b\u7de9\u306a\u3057\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7fa4\uff08E \u7fa4\uff09\u3067\u306f 10.8 mmol\/L \u306b\u5897\u52a0\u3057\u3066\u3044\u305f (<strong>Table 2<\/strong>). \u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u671f\u9593\u306e\u6700\u5f8c\u306b\u4e21\u7fa4\u9593\u306e\u5dee\u7570\u306f\u6e1b\u5c11\u3057\u305f\uff0e\u3086\u3048\u306b\uff0c\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u3092\u4f34\u3046\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u306e\u8840\u4e2d\u4e73\u9178\u6fc3\u5ea6\u306f\uff0c\u4ed5\u4e8b\u91cf\u304c\u4f4e\u3044\u306b\u3082\u304b\u304b\u308f\u3089\u305a\uff0c\u4f1d\u7d71\u7684\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u3088\u308a\u6e1b\u5c11\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u5927\u304d\u304f\u306a\u3063\u305f\uff0e<\/p>\n<p>\u3000\u8840\u4e2d\u3078\u306e\u7b4b\u539f\u6027\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bc\u653e\u51fa\u306f\u4f5c\u52d5\u7b4b\u306e\u7d30\u80de\u819c\u306e\u969c\u5bb3\u3092\u9593\u63a5\u7684\u306b\u53cd\u6620\u3057\u3066\u304a\u308a\uff0c\u8ca0\u8377\u91cf\u306b\u4f9d\u5b58\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u308b\uff0e\u4f8b\u3048\u3070\uff0c\u30a8\u30ad\u30bb\u30f3\u30c8\u30ea\u30c3\u30af\u904b\u52d5\u306b\u304a\u3051\u308b CK \u6d3b\u6027\u306e\u4e0a\u6607\u306f\u30b3\u30f3\u30bb\u30f3\u30c8\u30ea\u30c3\u30af\u904b\u52d5\u3088\u308a\u3082\u9065\u304b\u306b\u5927\u304d\u3044 (47,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/6631446\" rel=\"noopener\" target=\"_blank\">48<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/3951481\" rel=\"noopener\" target=\"_blank\">49<\/a>). \u6211\u3005\u306e\u8a66\u9a13 (46) \u306b\u304a\u3044\u3066\u306f\uff0c\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u671f\u9593\u306e\u7b2c 2 \u9031\u3067\u306e MMCK \u6d3b\u6027\u4e0a\u6607\u306f C \u7fa4\uff08\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff09\u3067\u306f E \u7fa4\uff08\u5f1b\u7de9\u306a\u3057\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff09\u3088\u308a 73% \u9ad8\u304b\u3063\u305f (258 &pm; 69 IU\/L vs. 149 &pm; 36 IU\/L). \u3053\u308c\u306f C \u7fa4\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u8ca0\u8377\u304c\u3088\u308a\u5927\u304d\u3044\u3053\u3068\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308b (85% 1RM vs. 50% 1RM). \u304a\u305d\u3089\u304f E \u7fa4\u306e\u88ab\u691c\u8005\u306b\u304a\u3044\u3066\uff0c\u4f5c\u52d5\u7b4b\u3067\u306e\u8840\u6d41\u906e\u65ad\u304c\u7b4b\u7dda\u7dad\u819c\u306e\u969c\u5bb3\u3092\u5897\u5f37\u3057\u306a\u304b\u3063\u305f\u306e\u3060\u308d\u3046\uff0e\u3053\u308c\u306f\u6b21\u306e\u77e5\u898b\u3068\u3082\u4e00\u8cab\u3057\u3066\u3044\u308b\uff0e\u3064\u307e\u308a\uff0c\u4f5c\u52d5\u3057\u3066\u3044\u308b\u56db\u80a2\u306e\u9589\u585e\u306f\u8840\u4e2d CK \u6d3b\u6027\u3092\u4e0a\u6607\u3055\u305b\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3042\u308b\uff0e214 mmHg \u306e\u5727\u529b\u3067\u4f5c\u52d5\u7b4b\u306e\u8840\u6d41\u3092\u906e\u65ad\u3057\u305f\u4f4e\u5f37\u5ea6 (20% 1RM) \u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7fcc\u65e5\u306b\u9589\u585e\u306a\u3057\u3067\u904b\u52d5\u3055\u305b\u305f\u5bfe\u7167\u7fa4\u3068\u540c\u7b49\u306e CK \u30ec\u30d9\u30eb\u3067\u3042\u3063\u305f (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10642363\" rel=\"noopener\" target=\"_blank\">20<\/a>). <\/p>\n<p>\u3000\u6211\u3005\u306e\u8a66\u9a13 (46) \u3067\u7528\u3044\u305f\u4e8c\u7a2e\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u8ca0\u8377\u306b\u304a\u3044\u3066\u4e73\u9178\u3068 MMCK \u6fc3\u5ea6\u5909\u5316\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\uff0c\u4ee5\u4e0b\u306e\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u305f\uff0e\u3064\u307e\u308a\uff0c\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u3088\u308a\u5927\u304d\u306a\u7b4b\u7dda\u7dad\u3078\u306e\u6a5f\u68b0\u7684\u969c\u5bb3\u3092\u3082\u305f\u3089\u3057\uff0c\u8840\u4e2d\u3078\u306e MMCK \u653e\u51fa\u306e\u5897\u52a0\u3092\u3082\u305f\u3089\u3059\uff0e\u540c\u6642\u306b\uff0c\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u306b\uff0c\u5f37\u5316\u3055\u308c\u305f\u89e3\u7cd6\u306f\u8840\u4e2d\u3078\u306e\u4e73\u9178\u306e\u8457\u660e\u306a\u84c4\u7a4d\u3092\u3082\u305f\u3089\u3059\uff0e\u3086\u3048\u306b\uff0c\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u4e3b\u306b\u6a5f\u68b0\u95a2\u9023\u523a\u6fc0\u3092\u751f\u6210\u3057\uff0c\u7b4b\u7dda\u7dad\u306b\u304a\u3051\u308b\u540c\u5316\u30d7\u30ed\u30bb\u30b9\u3092\u60f9\u8d77\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e\u4e00\u65b9\u3067\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306b\u306f\u4ee3\u8b1d\u6027\u5909\u5316\u304c\u3088\u308a\u5f37\u304f\u9032\u5c55\u3059\u308b\uff0e\u4eee\u306b\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u3067\u306e\u904b\u52d5\u306e\u4e3b\u306a\u6a5f\u80fd\u304c\u4f5c\u52d5\u7b4b\u306e\u8840\u6d41\u906e\u65ad\u3067\u3042\u308b\u3068\u4eee\u5b9a\u3059\u308b\u306a\u3089\uff0c\u7b4b\u80a5\u5927\u53cd\u5fdc\u306e\u6a5f\u5e8f\u3092\u8b70\u8ad6\u3059\u308b\u4e0a\u3067\uff0c\u9589\u585e\u72b6\u614b\u4e0b\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u306a\u304f\u3066\u306f\u306a\u3089\u306a\u3044\uff0e\u4f8b\u3048\u3070 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10879455\" rel=\"noopener\" target=\"_blank\">21<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8140900\" rel=\"noopener\" target=\"_blank\">22<\/a>) \u3067\u306f 4 \u9031\u9593\u306e\u5acc\u6c17\u7684\u904b\u52d5\uff08\u9031\u306b 4 \u56de 1 \u56de\u3042\u305f\u308a 45 \u5206\u9593\u30b5\u30a4\u30af\u30ea\u30f3\u30b0 \u8ca0\u8377~20% 1RM\uff09\u3092\u6c17\u5bc6\u5ba4\u5185\u306b\u3066\u884c\u3044\uff0c\u4e0b\u534a\u8eab\u3092 50 mmHg \u52a0\u5727\u3057\u305f\u7d50\u679c\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3057\u305f\u811a\u306e\u65ad\u9762\u7a4d\u304c\u5897\u52a0\u3057\uff0c\u305d\u308c\u306f\u4e3b\u306b I \u578b\u304a\u3088\u3073 IIB \u578b\u306e\u7b4b\u7dda\u7dad\u3067\u3042\u3063\u305f\uff0e\u8457\u8005\u3089\u306f\u7b4b\u80a5\u5927\u3092\u6b21\u306e\u4e8c\u3064\u3060\u3068\u307f\u306a\u3057\u3066\u3044\u308b\uff0e\u3064\u307e\u308a\uff0c<strong>\u53ce\u7e2e\u30bf\u30f3\u30d1\u30af\u306e\u5897\u52a0<\/strong>\u3068\uff0c<strong>\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u304a\u3088\u3073\u8d85\u6c34\u548c\u7269\u306e\u5897\u52a0<\/strong>\u3068\u3067\u3042\u308b\uff0e\u4f3c\u305f\u3088\u3046\u306a\u7d50\u679c\u304c\u30a8\u30ea\u30fc\u30c8\u30e9\u30b0\u30d3\u30fc\u9078\u624b\u3067 8 \u9031\u9593\u306e\u30ab\u30d5\u5727 200 mmHg \u3067\u306e\u865a\u8840\u6027\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u9031 2 \u56de, 1 \u56de 4 \u30bb\u30c3\u30c8, 50% 1RM\uff09\u3092\u884c\u3044\uff0c\u89b3\u5bdf\u3055\u308c\u3066\u3044\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11990743\" rel=\"noopener\" target=\"_blank\">50<\/a>). Dynamic Force \u306b\u304a\u3051\u308b\u5897\u52a0\u304a\u3088\u3073 MRI \u3067\u306e\u65ad\u9762\u7a4d\u5897\u52a0\u306f\u305d\u308c\u305e\u308c 14%, 15% \u3067\u3042\u3063\u305f\uff0e\u7279\u7570\u7684\u306a\u529b\u304a\u3088\u3073\u7b4b\u96fb\u56f3\u6d3b\u52d5\u306e\u5897\u52a0\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\uff0c\u8457\u8005\u3089\u306f\u7b4b\u4f53\u7a4d\u306e\u5897\u52a0\u306f\u4e3b\u306b\u53ce\u7e2e\u30bf\u30f3\u30d1\u30af\u306b\u3088\u308b\u3068\u306e\u7d50\u8ad6\u306b\u81f3\u3063\u305f\uff0e<\/p>\n<p>\u3000GH \u304a\u3088\u3073\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50 (IGF-1) \u306e\u5206\u6ccc\u5897\u52a0\u306f\uff0c\u8840\u6d41\u906e\u65ad\u306b\u5bfe\u6297\u3059\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u3088\u308b\u7b4b\u80a5\u5927\u53cd\u5fdc\u306e\u5468\u8fba\u56e0\u5b50\u3068\u8003\u3048\u3089\u308c\u308b\uff0e\u6211\u3005\u306e\u8a66\u9a13 (46) \u3067\u306f\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u306e\u8840\u4e2d GH \u6fc3\u5ea6\u306f\u9ad8\u304b\u3063\u305f\uff0e\u7b4b\u7dda\u7dad\u3078\u306e\u6a5f\u68b0\u7684\u52b9\u679c\u304c\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3088\u308a\u3082\u5c0f\u3055\u304b\u3063\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a (Table 2). \u5f1b\u7de9\u306a\u3057\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\uff0c\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30b5\u30a4\u30af\u30eb\u5168\u4f53\u3092\u901a\u3057\u3066\u9ad8\u3044 GH \u53cd\u5fdc\u3092\u3082\u305f\u3089\u3057\u305f\u3053\u3068\u306f\u91cd\u8981\u3067\u3042\u308b\uff0e\u8840\u4e2d GH \u306e\u6709\u610f\u306a\u5897\u52a0\u304c\u9759\u8108\u9589\u585e\u3092\u4f34\u3046\u5acc\u6c17\u6027\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u8a8d\u3081\u3089\u308c\u305f (<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs004210050369\" rel=\"noopener\" target=\"_blank\">10<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10642363\" rel=\"noopener\" target=\"_blank\">20<\/a>). \u8457\u8005\u3089\u306b\u3088\u308b\u3068\uff0c\u8840\u6d41\u3092\u5236\u9650\u3055\u308c\u3066\u4f5c\u52d5\u3057\u3066\u3044\u308b\u7b4b\u8089\u5185\u306e\u4ee3\u8b1d\u7523\u7269\u304c\u5c40\u6240\u7684\u306b\u84c4\u7a4d\u3057\u305f\u53cd\u5fdc\u306b\u304a\u3051\u308b\u6c42\u5fc3\u6027\u795e\u7d4c III \u304a\u3088\u3073 IV \u306e\u6d3b\u6027\u5316\u306b\u3088\u308b\u3068\u3044\u3046 (<strong>metaboreflex mechanism<\/strong>). <\/p>\n<p>\u3000\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u540c\u5316\u52b9\u679c\u306e\u30e1\u30a4\u30f3\u30b7\u30b9\u30c6\u30e0\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u306f IGF-1 \u3067\u3042\u308b\uff0e\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306b\u523a\u6fc0\u3055\u308c\u305f\u809d\u7d30\u80de\u306b\u3088\u308a\u5168\u8eab\u6027\u306b\u5206\u6ccc\u3055\u308c\uff0c\u53ce\u7e2e\u30bf\u30f3\u30d1\u30af\u6d3b\u52d5\u5f37\u5ea6\u306b\u3088\u308a\u9aa8\u683c\u7b4b\u7dda\u7dad\u304b\u3089\u30aa\u30fc\u30c8\u30af\u30e9\u30a4\u30f3\u306b\u5206\u6ccc\u3055\u308c\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16024511\" rel=\"noopener\" target=\"_blank\">51<\/a>). \u3086\u3048\u306b\uff0c\u8840\u4e2d IGF-1 \u306e\u5897\u52a0\u304c\u9ad8\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306b\u8a18\u9332\u3055\u308c\u305f (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2262468\" rel=\"noopener\" target=\"_blank\">12<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21053157\" rel=\"noopener\" target=\"_blank\">14<\/a>). \u6211\u3005\u306e\u8a66\u9a13 (46) \u3067\u306f\uff0c\u8840\u4e2d IGF-1 \u30ec\u30d9\u30eb\u306e\u5897\u52a0\u306f\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\uff08\u7b2c 2 \u9031\u304a\u3088\u3073\u7b2c 7 \u9031\uff09\u306b\u306e\u307f\u8a18\u9332\u3055\u308c\u305f\uff0e\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u3088\u308a\u5927\u304d\u306a\u6a5f\u68b0\u7684\u8ca0\u8377\u3092\u7279\u5fb4\u3068\u3059\u308b\uff09\u5f8c\u306b\u306f IGF-1 \u6fc3\u5ea6\u306b\u5909\u5316\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f (<strong>Table 2<\/strong>). \u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u306e\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e IGF-1 \u5897\u52a0\u306f GH \u5206\u6ccc\u5897\u52a0\u3092\u80cc\u666f\u3068\u3057\u3066\u8d77\u304d\u305f\u3053\u3068\u306f\u7279\u7b46\u3059\u3079\u304d\u3053\u3068\u3067\u3042\u308b (<strong>Table 2<\/strong>). <\/p>\n<p>\u3000\u8840\u6d41\u5236\u9650\u3092\u4f34\u3046\u4f4e\u5f37\u5ea6\u904b\u52d5\u306f\u8840\u4e2d\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u5024\u3092\u5897\u52a0\u3055\u305b\u306a\u304b\u3063\u305f (<strong>Table 2<\/strong>). \u305d\u308c\u306f\u4ed6\u306e\u8457\u8005\u3089\u306e\u30c7\u30fc\u30bf\u3068\u3082\u4e00\u81f4\u3057\u3066\u3044\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16902061\" rel=\"noopener\" target=\"_blank\">52<\/a>). \u540c\u6642\u306b\uff0c\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u904b\u52d5\u306f\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u5206\u6ccc\u3092\u5897\u52a0\u3055\u305b\uff0c\u305d\u308c\u306f\u660e\u3089\u304b\u306b\uff0c\u3053\u306e\u7a2e\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9ad8\u3044\u7269\u7406\u7684\u30b3\u30b9\u30c8\u3092\u793a\u5506\u3057\u3066\u3044\u308b (Table 2). <\/p>\n<p>\u3000\u3086\u3048\u306b\uff0c\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6 (50% 1RM) \u904b\u52d5\u306f\u9ad8\u30ec\u30d9\u30eb\u306e\u8840\u4e2d GH \u304a\u3088\u3073 IGF-1 \u5206\u6ccc\u3092\u3082\u305f\u3089\u3057\uff0c\u305d\u308c\u306f\u4f1d\u7d71\u7684\u65b9\u6cd5\u306e\u3088\u308a\u5927\u304d\u306a\u5916\u90e8\u8ca0\u8377 (85% 1RM) \u3088\u308a\u3082\u9ad8\u3044\uff0e\u304a\u305d\u3089\u304f\uff0c\u3053\u306e\u73fe\u8c61\u306f\u8840\u6d41\u6e1b\u5c11\u306b\u3088\u308b\u4e0d\u5b8c\u5168\u306a\u5f1b\u7de9\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u304a\u3051\u308b\u7b4b\u8089\u5185\u3078\u306e\u4ee3\u8b1d\u7269\u306e\u3088\u308a\u9ad8\u3044\u84c4\u7a4d\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308a\uff0c\u5fc5\u7136\u7684\u306b\uff0c\u3053\u306e\u7a2e\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u7b4b\u8089\u306e\u865a\u8840\u72b6\u614b\u4e0b\u3068\u540c\u7b49\u306b\u306a\u308b\uff0e\u3057\u304b\u3057\uff0c\u7279\u7b46\u3059\u3079\u304d\u3053\u3068\u3060\u304c\uff0c\u540c\u5316\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306e\u4e8b\u5f8c\u523a\u6fc0\u52b9\u679c\u306e\u4ee3\u8b1d\u53cd\u5c04\u306e\u6a5f\u5e8f\u306f\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\uff0e\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u5bfe\u3059\u308b\u30db\u30eb\u30e2\u30f3\u5fdc\u7b54\u306e\u7814\u7a76\u306b\u304a\u3044\u3066\uff0c\u7d50\u679c\u306f\u6df7\u4e71\u3057\u3066\u3044\u308b\uff0eWest \u3089\u306f\u7b4b\u529b\u5897\u52a0\u304a\u3088\u3073\u7b4b\u80a5\u5927\u306b\u5bfe\u3059\u308b\u8840\u4e2d\u5185\u56e0\u6027\u30db\u30eb\u30e2\u30f3\u306e\u30ec\u30d9\u30eb\u5dee\u3092\u7814\u7a76\u3057\u305f (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19910330\" rel=\"noopener\" target=\"_blank\">53<\/a>). \u8457\u8005\u3089\u306f\u3053\u3046\u7d50\u8ad6\u3057\u3066\u3044\u308b\uff0c\u3064\u307e\u308a\uff0c\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u3088\u308a\u8d77\u3053\u308b\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3068 IGF-1 \u30ec\u30d9\u30eb\u306e\u5897\u52a0\u306f\u7b4b\u80a5\u5927\u30d7\u30ed\u30bb\u30b9\u306e\u4e3b\u8981\u306a\u523a\u6fc0\u3067\u306f\u306a\u3044\u3068\uff0e\u7b4b\u30bf\u30f3\u30d1\u30af\u5408\u6210\u306e\u8abf\u7bc0\u306f\uff0c\u5f7c\u3089\u306b\u3088\u308c\u3070\uff0c\u4e3b\u306b\u7d30\u80de\u5185\u306e\u6a5f\u68b0\u7684\u30fb\u4ee3\u8b1d\u7684\u523a\u6fc0\u306b\u3088\u308b\u3068\u3044\u3046\uff0e<\/p>\n<h4>Effects of high-intensity strength training and low-intensity strength training without relaxation of muscles on the expression of genes regulating myogenesis. <\/h4>\n<p>\u3000\u904e\u53bb\u5341\u5e74\u9593\u3067\u5206\u5b50\u751f\u7269\u5b66\u7684\u624b\u6cd5\u306f\uff0c\u591a\u69d8\u306a\u8eab\u4f53\u6d3b\u52d5\u306b\u7b4b\u8089\u304c\u9069\u5fdc\u3059\u308b\u6a5f\u5e8f\u3092\u89e3\u660e\u3057\uff0c\u7570\u306a\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u52b9\u7387\u3092\u5b9a\u7fa9\u3059\u308b\u306e\u306b\u5e83\u304f\u7528\u3044\u3089\u308c\u3066\u304d\u305f\uff0e\u7b4b\u7d30\u80de\u3067\u767a\u73fe\u3057\u3066\u3044\u308b\u907a\u4f1d\u5b50\u3092\u89e3\u6790\u3059\u308b\u3053\u3068\u3067\uff0c\u500b\u3005\u306e\u88ab\u9a13\u8005\u306b\u72ec\u7acb\u306b\uff0c\u4e00\u3064\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u306e\u7d50\u679c\u306b\u57fa\u3065\u3044\u3066\uff0c\u7570\u306a\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30c8\u30b3\u30eb\u306e\u52b9\u7387\u3092\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u3063\u305f\uff0e1 \u30bb\u30c3\u30b7\u30e7\u30f3\u306e\u9ad8\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\uff0c\u56de\u5fa9\u65e5\u3068\u3088\u308a\u9577\u3044\u671f\u9593\u306b\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\uff0e\u4f8b\u3048\u3070 IGF-1, MGF, MyoD, Myogenin, \u305d\u3057\u3066\u30df\u30aa\u30b9\u30bf\u30c1\u30f3 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18818249\" rel=\"noopener\" target=\"_blank\">54<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15618316\" rel=\"noopener\" target=\"_blank\">55<\/a>). \u8840\u6d41\u5236\u9650\u3092\u4f34\u3046\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (20% 1RM) \u304c\u7814\u7a76\u3055\u308c\u305f\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5909\u5316\u306b\u81f3\u308b\u3053\u3068\u3082\u5206\u304b\u3063\u305f\uff0e\u540c\u3058\u5f37\u5ea6\u3067\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3057\u305f\u5bfe\u7167\u7fa4\u306b\u304a\u3044\u3066\u306f\uff0c\u767a\u73fe\u306e\u5909\u5316\u306f\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u306e\u3067\u3042\u308b\u304c (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18317375\" rel=\"noopener\" target=\"_blank\">56<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20653608\" rel=\"noopener\" target=\"_blank\">57<\/a>). \u3053\u308c\u306f\u6b21\u306e\u4e8b\u5b9f\u306b\u3088\u308b\uff0e\u3064\u307e\u308a\uff0c\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\uff0c\u3088\u308a\u5927\u304d\u306a\u5916\u90e8\u8ca0\u8377 (70-90% 1RM) \u304c\u4e3b\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u3066\u3044\u308b\uff0e\u4e00\u65b9\uff0c\u5f15\u7528\u3057\u305f\u8a66\u9a13\u3067\u306f\uff0c\u5bfe\u7167\u7fa4\u3068\u3057\u3066 20% 1RM \u306e\u8ca0\u8377\u304c\u7528\u3044\u3089\u308c\u3066\u304a\u308a\uff0c\u305d\u306e\u7a0b\u5ea6\u306e\u8ca0\u8377\u3067\u306f\u8eab\u4f53\u6d3b\u52d5\u306e\u6d3b\u767a\u306a\u4eba\u306b\u306f\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u5909\u5316\u3055\u305b\u308b\u306b\u306f\u5c0f\u3055\u3059\u304e\u308b\u306e\u304b\u3082\u77e5\u308c\u306a\u3044\uff0e\u4e0a\u8ff0\u3057\u305f\u3088\u3046\u306b\uff0c\u8840\u6d41\u3092\u906e\u65ad\u3057\u305f\u904b\u52d5\u3067\u4f5c\u52d5\u7b4b\u306b\u8457\u660e\u306a\u4ee3\u8b1d\u30b9\u30c8\u30ec\u30b9\u3092\u9054\u6210\u3059\u308b\u306b\u306f\u8ca0\u8377\u306f\u5c11\u306a\u304f\u3068\u3082 30-40% 1RM \u3067\u3042\u308b\u3079\u304d\u3060 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20360434\" rel=\"noopener\" target=\"_blank\">25<\/a>). \u3086\u3048\u306b\uff0c\u6211\u3005\u306f\u7b4b\u5f1b\u7de9\u306a\u3057\u306e\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (50% 1RM) \u5f8c\u306e\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5909\u5316\u3068\uff0c\u4f1d\u7d71\u7684\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u5909\u5316\u3068\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u306b\u3057\u305f\uff0e<\/p>\n<p>\u3000\u904b\u52d5\u6642\u306e\u7570\u306a\u308b\u7b4b\u7fa4\u9593\u306e\u8ca0\u8377\u306e\u518d\u5206\u914d\u52b9\u679c\u3092\u6392\u9664\u3059\u308b\u305f\u3081\uff0c\u307e\u305f\u7d30\u80de\u5185\u30b7\u30b0\u30ca\u30ea\u30f3\u30b0\u306e\u540c\u5316\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u5897\u52a0\u306e\u30a4\u30f3\u30d1\u30af\u30c8\u3092\u6392\u9664\u3059\u308b\u305f\u3081\u306b\uff0c\u30cb\u30fc\u30a8\u30af\u30b9\u30c6\u30f3\u30b7\u30e7\u30f3\u304c\u9078\u3070\u308c\u305f\uff0e\u5c0f\u3055\u306a\u7b4b\u4f53\u7a4d\u306e\u95a2\u4e0e\u3059\u308b\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\u540c\u5316\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u5897\u52a0\u306b\u3064\u306a\u304c\u3089\u306a\u3044 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19910330\" rel=\"noopener\" target=\"_blank\">53<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11782267\" rel=\"noopener\" target=\"_blank\">58<\/a>) \u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\uff0e\u4eca\u56de\u306e\u8a66\u9a13\u3067\u306f\uff0c\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (50% 1RM) \u306b\u304a\u3044\u3066\uff0c\u6bdb\u7d30\u8840\u7ba1\u5185\u306e\u4e73\u9178\u6fc3\u5ea6\u304c\u308f\u305a\u304b\u306b\u4e0a\u6607\u3057\u305f (3.1 &pm; 0.5 mmol\/L). \u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30b7\u30e7\u30f3\u5f8c\u306b\u306f 6.3 &pm; 0.6 mmol\/L \u306b\u307e\u3067\u4e0a\u6607\u3057\u305f\uff0e\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306b\u306f\u4e73\u9178\u6fc3\u5ea6\u306f\u6700\u9ad8\u5024\u306b\u9054\u3057\u305f (7.4 &pm; 0.5 mmol\/L). \u4e88\u60f3\u3055\u308c\u305f\u3088\u3046\u306b\uff0c\u540c\u5316\u30db\u30eb\u30e2\u30f3\u306e\u542b\u6709\u91cf\u3067\u3042\u308b\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3068 IGF-1 \u306f 8 \u9031\u9593\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u3067\u3055\u3048\u5909\u5316\u3057\u306a\u304b\u3063\u305f\uff0eGH \u306e\u542b\u6709\u91cf\u306f\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306b\u308f\u305a\u304b\u306b\u5897\u52a0\u3057\u305f\uff0e<\/p>\n<p>\u3000\u4eca\u65e5\u306e\u7dcf\u8aac\u306b\u3088\u308b\u3068\uff0c\u6210\u4eba\u306b\u304a\u3044\u3066\u306f\uff0c<strong>IGF-1 \u86cb\u767d\u306f\u9aa8\u683c\u7b4b\u304b\u3089\u5206\u6ccc\u3055\u308c\uff0c\u7b4b\u80a5\u5927<\/strong>\u3092\u8d77\u3053\u3057\u3046\u308b\uff0e\u3053\u308c\u306f\u4e3b\u306b<strong>\u30b5\u30c6\u30e9\u30a4\u30c8\u7d30\u80de\u306e\u5206\u5316<\/strong>\u3068<strong>\u65e2\u5b58\u306e\u7b4b\u7dda\u7dad\u3078\u306e\u878d\u5408<\/strong>\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15302582\" rel=\"noopener\" target=\"_blank\">59<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17264150\" rel=\"noopener\" target=\"_blank\">60<\/a>). \u3055\u3089\u306b\uff0c<strong>IGF-1 \u306b\u3088\u308b\u7b4b\u86cb\u767d\u7570\u5316\u306e\u6291\u5236<\/strong>\u52b9\u679c\u3068\u3057\u3066 <strong>Akt-FOXO \u30b7\u30b0\u30ca\u30eb\u7d4c\u8def<\/strong> (61) \u304c\u3042\u308a\uff0c<strong>Akt-mTORC1 \u306e\u6d3b\u6027\u5316\u306b\u3088\u308b\u30bf\u30f3\u30d1\u30af\u5408\u6210\u7387\u306e\u5897\u52a0<\/strong>\u304c\u8b70\u8ad6\u3055\u308c\u3066\u3044\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17264150\" rel=\"noopener\" target=\"_blank\">60<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11715022\" rel=\"noopener\" target=\"_blank\">62<\/a>). \u6211\u3005\u306e\u8a66\u9a13\u3067\u306f\uff0c\u56de\u5fa9\u671f\u306b\u304a\u3051\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50 (IGF-1Ea) \u7b4b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u306e\u767a\u73fe\u306f\u5909\u5316\u3057\u3066\u3044\u306a\u304b\u3063\u305f (<strong>Fig. 2<\/strong>). <\/p>\n<figure id=\"attachment_2942\" aria-describedby=\"caption-attachment-2942\" style=\"width: 156px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Fig2-1.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Fig2-1-156x300.png\" alt=\"\" width=\"156\" height=\"300\" class=\"size-medium wp-image-2942\" srcset=\"https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Fig2-1-156x300.png 156w, https:\/\/www.muscle-hypertrophy.com\/wp-content\/uploads\/2018\/06\/Fig2-1.png 506w\" sizes=\"auto, (max-width: 156px) 100vw, 156px\" \/><\/a><figcaption id=\"caption-attachment-2942\" class=\"wp-caption-text\">Fig. 2. The expression of mRNA of IGF 1Ea (a) and myostatin (b) normalized to the baseline levels, after a single strength training: traditional high-intensity strength training (75% of 1 RMtr), low-intensity training without relaxation (50% of 1 RM no relax), and traditional low-intensity training (50% of 1 RMtr). 0 h, the time of the termination of a training session. * Significant changes (p &le; 0.05), compared to the baseline levels; # significant difference (\u0440 \u2264 0.05) from the respective parameter of 75% of 1 RM and 50% of 1 RM<\/figcaption><\/figure>\n<p>\u3000\u7b4b\u8089\u306e\u6210\u9577\u306e\u6291\u5236\u7684\u306a\u8abf\u7bc0\u56e0\u5b50\u3067\u3042\u308b\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3078\u306e\u5f71\u97ff\u3092\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30ec\u30b8\u30e1\u30f3\u9593\u3067\u6bd4\u8f03\u3057\u305f\uff0e<strong>\u5f1b\u7de9\u306a\u3057\u306e\u904b\u52d5\u5f8c 5 \u6642\u9593\u3067\u30df\u30aa\u30b9\u30bf\u30c1\u30f3 mRNA \u6fc3\u5ea6\u306f 4 \u5206\u306e 1 \u306b\u4f4e\u4e0b\u3057\uff0c\u3055\u3089\u306b\u904b\u52d5\u5f8c 22 \u6642\u9593\u307e\u3067\u305d\u306e\u30ec\u30d9\u30eb\u304c\u6301\u7d9a<\/strong>\u3057\u305f (<strong>Fig. 2<\/strong>). <strong>\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5f8c\u3067\u306f\uff0c\u30df\u30aa\u30b9\u30bf\u30c1\u30f3 mRNA \u6fc3\u5ea6\u306f\u56de\u5fa9\u671f\u306e 22 \u6642\u9593\u5f8c\u307e\u3067\u6301\u7d9a\u7684\u306b\u4f4e\u4e0b\u3057\u305f<\/strong>\uff08\u30c8\u30fc\u30bf\u30eb\u3067 20 \u5206\u306e 1 \u307e\u3067\uff09\uff0e\u7279\u7b46\u3059\u3079\u304d\u3053\u3068\u3060\u304c\uff0c\u4f4e\u5f37\u5ea6\u306e\u4f1d\u7d71\u7684\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u3067\u306f\uff0c\u3053\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u306f\u5909\u5316\u304c\u306a\u304b\u3063\u305f\uff0e<strong>\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u4f4e\u4e0b\u306f Akt-mTORC1 \u7d4c\u8def\u306e\u30b7\u30b0\u30ca\u30eb\u30ad\u30ca\u30fc\u30bc\u6d3b\u6027\u306e\u5897\u52a0\u306b\u95a2\u9023<\/strong>\u3057\u3066\u3044\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18801898\" rel=\"noopener\" target=\"_blank\">63<\/a>) \u4e00\u65b9\u3067\uff0c\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u767a\u73fe\u4f4e\u4e0b\u306f FOXO \u8ee2\u5199\u56e0\u5b50\u306e\u6d3b\u6027\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a, mRNA \u30ea\u30ac\u30fc\u30bc E3 \u306e\u767a\u73fe\u3092\u523a\u6fc0\u3057\u3066\u30b5\u30c6\u30e9\u30a4\u30c8\u7d30\u80de\u306e\u5206\u5316\u3092\u963b\u5bb3\u3059\u308b (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16883577\" rel=\"noopener\" target=\"_blank\">64<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20602111\" rel=\"noopener\" target=\"_blank\">65<\/a>). <\/p>\n<p>\u3000\u3086\u3048\u306b\uff0c\u30e2\u30fc\u30c9\u306e\u7570\u306a\u308b\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u7570\u306a\u308b\u7d50\u679c\u3068\u306a\u308b\uff0e\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3088\u308a\u3082\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u767a\u73fe\u304c\u5927\u304d\u304f\u4f4e\u4e0b\u3059\u308b\uff0e\u660e\u3089\u304b\u306b\uff0c\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u7570\u306a\u308b\u578b\u306e\u52b9\u679c\u3092\u8a73\u7d30\u306b\u7279\u5fb4\u3065\u3051\u308b\u305f\u3081\u306b\uff0c\u7b4b\u539f\u7dda\u7dad\u30bf\u30f3\u30d1\u30af\u5408\u6210\u7387\u306e\u5909\u5316\u3068\uff0c\u30bf\u30f3\u30d1\u30af\u5408\u6210\u7387\u3092\u8abf\u7bc0\u3059\u308b\u30b7\u30b0\u30ca\u30eb\u7d4c\u8def\u306e\u6d3b\u6027\u5316\u3092\u8a55\u4fa1\u3057\u306a\u304f\u3066\u306f\u306a\u3089\u306a\u3044\uff0e\u3053\u308c\u3089\u306e\u8ab2\u984c\u306f\u5c06\u6765\u306e\u7814\u7a76\u304c\u89e3\u6c7a\u3059\u3079\u304d\u3067\u3042\u308b\uff0e<\/p>\n<h3>CONCLUSIONS<\/h3>\n<p>\u3000\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u7570\u306a\u308b\u578b\u306e\u52b9\u7387\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\u6b21\u306e\u3053\u3068\u304c\u793a\u3055\u308c\u305f\uff0e\u3059\u306a\u308f\u3061\uff0c\u4f5c\u52d5\u7b4b\u306e\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (50% 1RM) \u5f8c\u306b\u304a\u3044\u3066\u306f\uff0c\u7b4b\u529b\u306e\u80fd\u529b\u306e\u5897\u52a0\u3068\u4f5c\u52d5\u7b4b\u306e\u30b5\u30a4\u30ba\u306e\u5897\u52a0\u3068\u306f\u4f1d\u7d71\u7684\u306a\u9ad8\u5f37\u5ea6\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0 (80-85% 1RM) \u307b\u3069\u306b\u306f\u5927\u304d\u304f\u306a\u3044\uff0e\u7b4b\u80a5\u5927\u306f\u4f1d\u7d71\u7684\u306a\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u3082\u5f1b\u7de9\u306a\u3057\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u3082\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u304c\uff0c\u660e\u3089\u304b\u306b\u7570\u306a\u308b\u7d4c\u8def\u3067\u9054\u6210\u3055\u308c\u308b\uff0e\u4f1d\u7d71\u7684\u306a\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\uff0c\u6a5f\u68b0\u7684\u523a\u6fc0\u306f\u7b4b\u7dda\u7dad\u306b\u540c\u5316\u30d7\u30ed\u30bb\u30b9\u3092\u60f9\u8d77\u3057\uff0c\u4e3b\u306b\u751f\u6210\u3055\u308c\u308b\uff0e\u5f1b\u7de9\u306a\u3057\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\uff0c\u7b4b\u8089\u306b\u304a\u3051\u308b\u5acc\u6c17\u53cd\u5fdc\u306e\u6d3b\u6027\u5316\u304c\u660e\u767d\u306b\u306a\u308c\u3070\u306a\u308b\u307b\u3069\uff0c\u4ee3\u8b1d\u53cd\u5fdc\u306e\u7d50\u679c\u3068\u3057\u3066\u8840\u4e2d GH, IGF-1 \u304a\u3088\u3073\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5206\u6ccc\u5897\u52a0\u304c\u660e\u767d\u306b\u306a\u308b\uff0e\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3068\u7b4b\u5f1b\u7de9\u306a\u3057\u306e\u4f4e\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\uff0c\u7b4b\u5f62\u6210\u8abf\u7bc0\u907a\u4f1d\u5b50\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u767a\u73fe\u306e\u52d5\u614b\u306e\u9055\u3044\u306b\u3088\u308a\u7279\u5fb4\u3065\u3051\u3089\u308c\u308b\uff0e\u30c8\u30ea\u30ac\u30fc\u6a5f\u69cb\u306e\u9055\u3044\u306f\uff0c\u4e8c\u7a2e\u985e\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5f71\u97ff\u4e0b\u3067\u306e\u80a5\u5927\u6027\u5909\u5316\u306e\u7279\u5fb4\u306e\u9055\u3044\u3068\u7d44\u307f\u5408\u308f\u305b\u3089\u308c\u308b\uff0e\u53e4\u5178\u7684\u306a\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\uff0c\u65ad\u9762\u7a4d\u306b\u5360\u3081\u308b II \u578b\u7b4b\u7dda\u7dad\u306e\u512a\u5148\u7684\u306a\u5897\u52a0\u3092\u8a8d\u3081\u308b\uff0e\u5f1b\u7de9\u306a\u3057\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u306f\uff0c\u65ad\u9762\u7a4d\u3067\u306f I \u578b\u7b4b\u7dda\u7dad\u306e\u512a\u5148\u7684\u306a\u5897\u52a0\u3092\u8a8d\u3081\u308b\uff0e<\/p>\n<p>\u3000\u672c\u8a66\u9a13\u306f\u30b9\u30dd\u30fc\u30c4\uff0c\u7279\u306b\u7b4b\u529b\u3068\u6b69\u884c\u7b4b\u306e\u6301\u4e45\u529b\u304c\u9ad8\u5ea6\u306b\u8981\u6c42\u3055\u308c\u308b\u30b9\u30dd\u30fc\u30c4\u306e\u5b9f\u8df5\u306b\u304a\u3044\u3066\u6709\u7528\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e\u3055\u3089\u306b\uff0c\u76f8\u5bfe\u7684\u306b\u4f4e\u8ca0\u8377\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u976d\u5e2f\u3092\u640d\u50b7\u304b\u3089\u4fdd\u8b77\u3059\u308b\uff0e\u3053\u306e\u7279\u5fb4\u306f\u3053\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30ec\u30b8\u30e1\u30f3\u304c\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u53ca\u3073\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u533b\u5b66\u306b\u6709\u7528\u3068\u306a\u308b\u3053\u3068\u3092\u53ef\u80fd\u306b\u3057\uff0c\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u5916\u50b7\u5f8c\u306e\u7b4b\u306e\u904b\u52d5\u8010\u5bb9\u80fd\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u65b9\u6cd5\u3068\u540c\u3058\u304f\u3089\u3044\u5b89\u5168\u3067\u3042\u308b\uff0e<\/p>\n<h3>REFERENCES<\/h3>\n<p>1. 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